Manip - do it!  As a Microsoft employee, I did not have the 4.0 out of 4.0 grade average at University or a ton of computer experience before getting into the business; but I did have passion which Microsoft really appreciates.  If you want something, always go for it.  The only time that you don't want to do it is if you are just spamming interviews just to get in the door (typically this is a bad thing since the person doesn't want the job you are interviewing them for, but they just want to get the foot in to get into something else).

When I interview folks, I usually value passion (tempered with reality) over a grade point average.

So if you really want it, go for it!  Good luck!