Depends on the resolution frankly. I've been doing .NET and native Win32 work on a 14.1" Lenovo for years. Literally: a T40 and now a T60p.
In both cases, however, I had the 1400x1050 screen. Maximize VS to full screen and it's good to go.
At least that my take on it... resolutions and screen sizes are always subjective ![]()