Right click, Run as administrator.  Never have to turn UAC off and limit your exposure to the smallest possible attack vector.  For file level stuff, do this on explorer.  For other things you might want to do this with a command prompt and execute stuff from there.  Just be sure to close elevated processes as soon as possible.

BTW, UAC isn't "protecting the user from themselves".  If you're computer is internet facing, you run the risk of being hacked.  If UAC is off and you're running as an admin, the hacker has complete access to your computer.  With UAC on, you only get prompted when doing admin level stuff, and that should be rare enough that you could rarely care less, especially when you can employ "Run as administrator" tricks for more serious administrative tasks.