RLO said:

Tfraser, I assume that the reason you have this complaint is that you are manually adjusting lab computers in your job environment, and as such you are going to every machine and applying these adjustments?  Hence your complaints about the mouse? 

I'm pretty sure most of the mouse software packages (IntelliPoint, Logitech's SetPoint, etc) let you change this behavior.  Don't think Windows has a built-in option for it though.