I use Chrome because it's the fastest. Searching from the same bar used for websites is very convenient. It has a very slick, doesn't get in your way, GUI.
Except that it does get in my way. Putting tabs across the tops makes it so that I can't use Aero Snap. I like being able to blindly grab a window and whip it onto another monitor. I spent a weekend helping somebody transfer files, email and whatnot onto a new laptop. Somebody had told them to use Chrome. It was so hard, I almost had to scream.