In theory you can do just about anything. But when you apply for a job they want you to be productive in Visual Studio. Noone cares that you're a wizbang with Emacs hand coding MSIL. Get real.
Funny, where I work we don't care if people know VS when we interview. We presume that anyone can learn an IDE and we only worry that you know the languages we use and that you have some other knowledge that is useful to our team. Of our last three or four hires, only one had prior experience with VS and that was while working on XBox games. Come to think of it, they could be working with emacs right now. I wouldn't know since it only matters that their code functions.
Do you actually list Visual Studio as part of your skill set?