I do not see Bill's involvement in foreign societies as completely benign and benevolent. Not that he is trying to do harm but the population of the nations he helps are growing unsustainably. And the political pressure Bill and other tech leaders apply to support open borders immigration policies arguably cause a brain drain in poor countries. I think a good case can be made that if nations were left to develop on their own that they would be better off in the long run.
Keep in mind, the prime directive was written for a reason.