, elmer wrote

*snip*

Not if you are using an Exchange server released in the last decade.

Exchange 2003 supports Outlook 2000, as does Exchange 2007 if you configure it right (source: personal experience).

The compatibility matrix on TechNet is a bit inaccurate.:http://technet.microsoft.com/en-us/library/ff728623(v=exchg.141).aspx