@JoshRoss: Win 8 JavaScript development will last shorter than Silverlight did. These is no doubt that JavaScript is to gain popularity. I have written a few MVC apps, and they are just much crisper and better to use than webforms .
The jury is out with Metro, we look to be developing several new WPF client apps in desktop land, as it will be a few years before the people that pay for large software products will consider developing Metro apps.
I hope Microsoft choose something and stick to it for once.