I have two persistent bugs in VS2012
if the startup project is config manager platform "any cpu", when starting in debug mode I get a "remote endpoint was unreachable" error. I get that error sometimes. The fix is to change the platform from the any cpu default to x86.
This one started recently. Maybe it is something I am doing. When I CTRL-TAB to see the open files in a project I see the same file opened multiple times.