@Charles: Haven't had a chance to install yet (bathroom renovations take precedence), but from what I've seen it looks nice. I'm curious how the Metro UI performs with a mouse and keyboard. From what I've seen and read, it looks like it might be clunky. Is MS planning on releasing a touchpad mouse thing to add touch features to non-touchscreen monitors?

As far as the developer side goes, WinRT is a great idea. I'll have to play around with the dev tools, but maybe someone else can answer this. Can I have a WinRT app that utilizes .NET assemblies? Like something with a Metro UI but using ADO.NET to get data? Or an immersive window hosting a WPF user control?