Compared with lexical analysis, parsing, semantic checking, and of course doing all of this inside tooling, and then optimization, I've considered the emit phase of a compiler to be fairly straightforward.  Unless there are significant advantages in the area of optimization, I wouldn't expect building a compiler to be affected largely by the choice of RISC or CISC.

And I can't consider Intel vs. PowerPC to show the advantages or disadvantages of either platform.  I'm sure that if Apple chose Intel and Microsoft/IBM chose PowerPC, we would all be using PowerPC computers right now.  We might even be using PowerPC phones and tablets instead of ARM.