No http handler was found for request type 'GET'

Executing a python script in via ASPX in IIS7 via

Server.Execute("scriptname.py?arg1=x&arg2=z")

Gives me the following error:

No http handler was found for request type 'GET'

[HttpException (0x80004005): No http handler was found for request type 'GET']
   System.Web.HttpApplication.MapIntegratedHttpHandler(HttpContext context, String requestType, VirtualPath path, String pathTranslated, Boolean useAppConfig, Boolean convertNativeStaticFileModule) +849
   System.Web.HttpServerUtility.Execute(String path, TextWriter writer, Boolean preserveForm) +463

[HttpException (0x80004005): Error executing child request for ~/CGI-BIN/Stock-chart.py.]
   System.Web.HttpServerUtility.Execute(String path, TextWriter writer, Boolean preserveForm) +816
   System.Web.HttpServerUtility.Execute(String path) +8
   ms_sandbox.About.Page_Load(Object sender, EventArgs e) in D:\Dropbox\Dropbox\WebSites\ms-sandbox\ms-sandbox\About.aspx.cs:14
   System.Web.Util.CalliHelper.EventArgFunctionCaller(IntPtr fp, Object o, Object t, EventArgs e) +14
   System.Web.Util.CalliEventHandlerDelegateProxy.Callback(Object sender, EventArgs e) +35
   System.Web.UI.Control.OnLoad(EventArgs e) +91
   System.Web.UI.Control.LoadRecursive() +74
   System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint) +2207


I have added the script handler to IIS and I can call the script directly fine. 
It's only when I try to call it via server.execute that I have this issue. 

Any Ideas?

have you tried it with a full path?

can you execute any asp script using that Server.Execute() just to eliminate the python aspect of the problem?

maybe your app pool identity needs to be in iis_iusr group (total guess there).

@itsnotab

Asp Scripts execute fine and I've already set the app pool to run under an escalated account.

Really, not sure why my name is now WTF though....

Check your web.config setting.

  <system.webServer>
    <handlers>
        <add name="cgi-bin" 
         path="*.py" 
         verb="*" 
         modules="CgiModule" 
         scriptProcessor="C:\Python\python.exe %s %s" 
         resourceType="Unspecified" />
    </handlers>
  </system.webServer>

Have you enabled verb "GET" (or just use wildcard "*") for extension ".py"? (Make sure you've modified the scriptProcessor attribute above to match your python path.)