Yeah you are right @spivonious but the thing is I want to add facility to change the displayed data by changing mapping in database.

For example,

Combobox which displays names of Doctors who work in clinic, now I want to show list of doctors which are visiting doctors in same combobox instead of previous list.(plz assume labels and other things are in perfect sync to do this). For this thing I need to change column of Datasource Bound with this combobox. 

I want to achieve this by changing binding through server using data stored in database.

I hope I am making it little more clear about my scenario.