Well I don't like the skeuomorphic designs they used for the interface they showed off in the video, its a bit tacky even in 3D ... glass pane behind the tiles, tool chest, etc ... I think they have to dial it down and find something elegant, at least something for serious apps. It would probably end up being something flatter, like in Minority Report. Kids apps that stuff is okay, I guess.
That's skeumorphism though. Which, granted, may be necessary for now as people are learning new UI paradigms that may arise from this, but a 3D UI doesn't necessarily have to be skeumorphic.