The Enterprise Library 2.0 offers Visual Studio 2005 Smart Clients all the plumbing needed to quickly create a laptop -distributed system. This Library has capability for your application to know when it is online and to find your webservice and use it, all in its own set of threads. There's a lot more in the Library, too. It's a jaw dropper.
Combine it with
Click-once and you've got a system that will create buy-in and corporate confidence.