Thanks Duncan, but I'm not sure that's the problem. I downloaded the full wmv from the link above (and checked the version I originally pushed through), and I don't see the sync issues, which makes me think it's a streaming issue. When we produced the content, we made sure the camtasia capture and the video/audio from the camera are within 2-3 milliseconds of eachother in sync.
MetalJon, can you provide some more information? Is it that the audio of Karen talking is out of sync with the video of her talking? Or is it like Duncan states where the audio is out of sync with the PIP? if the second, is the audio also out of sync with her lips in the PIP?
Also, for a full video format, there is a download link above under downloads where you can download the non-streaming version of the video.