In this video, Dr. Peter Ernst of CoCreate (a Microsoft Partner in Germany) demonstrates how their One Space Designer product is tightly integrated with Sharepoint to enable bi-directional communication between a CAD application and Sharepoint workspaces. A custom panel within One Space Designer provides live interoperability with MOSS including task lists, RSS feeds, and other functionality.
The custom UI panel is deliberately modeled after Office's Tools -> Shared Workspace interface, so from the user's perspective it feels like you're in Microsoft Office without ever leaving CoCreate's solid modeling application. There is a lot of complexity under the surface that makes it all possible, but Dr. Ernst goes through a very simple demo scenario that makes the benefits of this approach easy to see and understand.
For more information about CoCreate, see www.cocreate.com. For more information about building Office Business Applications, see the MSDN whitepaper "Building Office Business Applications: A New Breed of Business Applications Built on the 2007 Microsoft Office System".