As someone that has to do a lot of presentations, I absolutely loved Don's advice. His take on not relying on the slides, and engaging the audience are (I'm afraid) all to often ignored in so many of the presentations I watch.
Another person that does excellent presentations and embodies all of what Don says in this video is Prof. Lessig - his presentations are legendary (just the white typewriter text on a black background is his "signature"). I've found it really hard to find
his talks online, but if anyone want to view an excellent example visit